Gene interactions and pathways from curated databases and text-mining

◀ Back to MAP2K6

MAP2K6 — TGFB1

Pathways - manually collected, often from reviews:

  • OpenBEL Selventa BEL large corpus: MAP2K6 → TGFB1 (increases, TGFB1 Activity)
    Evidence: up-regulation of BGN mRNA was preceded by a delayed increase in the phosphorylation of p38 and its upstream activator MKK6 in TGF-beta 1-treated PANC-1 cells,

Text-mined interactions from Literome

Kivinen et al., Cell Growth Differ 1999 : Ras- and mitogen activated protein kinase kinase dependent and -independent pathways in p21Cip1/Waf1 induction by fibroblast growth factor-2, platelet derived growth factor, and transforming growth factor-beta1
Ogihara et al., J Biol Chem 2003 : Instead, activin A and HGF activation was inhibited by overexpression of a dominant negative mutant of transforming growth factor-beta activated kinase 1 ( TAK1 ), or mitogen activated protein kinase kinase 3 ( MKK3 ), or by treatment with a p38 MAPK-specific inhibitor, SB203580