◀ Back to IRF1

EIF2AK2 — IRF1

Pathways - manually collected, often from reviews:

• KEGG Hepatitis C: EIF2AK1/EIF2AK2/EIF2AK3/EIF2AK4 → IRF1 (protein-protein, activation)

Text-mined interactions from Literome

Kirchhoff et al., Oncogene 1995 : IRF-1 induced cell growth inhibition and interferon induction requires the activity of the protein kinase PKR ... It is shown here that activation of the IRF-1 causes induction of PKR expression
Beretta et al., Oncogene 1996 (Leukemia) : Consequently, we investigated the role of IRF-1 in PKR expression ... We demonstrate that upregulation of IRF-1 expression in U937 cells by transfection is sufficient to induce PKR expression ... These results show that IRF-1 activates PKR expression and suggest that loss of one allele of the IRF-1 gene is sufficient to affect PKR expression