Gene interactions and pathways from curated databases and text-mining

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IL2RA — PTX4

Text-mined interactions from Literome

Jewett et al., J Clin Immunol 1994 : Also, PTX inhibited IL-2 triggered upregulation of the expression of CD69, CD25 , ICAM-1, and p75TNF-R on the cell surface
González-Amaro et al., J Immunol 1998 : PTX had a significant inhibitory effect on the T lymphocyte expression of the activation Ags CD25 ( IL-2R alpha-chain ), CD69 ( activation-inducer molecule ), and CD98 ( 4F2 ) induced by PHA
Richard et al., Int J Immunopharmacol 1998 : The effects of PTX, RAP, A77 1726, PTX/RAP, or PTX/A77 1726 ( at concentrations approximating the IC50 of individual drugs for inhibition of lymphoproliferation ) on anti-CD3 activated killer ( AK ) cell induction, CD25 expression, and interleukin (IL)-2 synthesis in anti-CD3 activated spleen cell cultures were also determined