Gene interactions and pathways from curated databases and text-mining

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IL1A — TNC

Text-mined interactions from Literome

Kuriyama et al., Hepatology 2011 (Reperfusion Injury) : The lack of Tnc expression resulted in impaired leukocyte recruitment and decreased expressions of interleukin (IL)-1ß , IL-6, and CXCL2 after liver reperfusion
Maqbool et al., Matrix Biol 2013 : In contrast, multiple signaling pathways ( p38, JNK, PI3K/Akt and NF?B ) contributed to IL-1a induced TNC expression ... In conclusion, IL-1a reduced CCN2 expression and increased TNC expression in human CF. These observations are of potential value for understanding how inflammation and ECM regulation are linked at the level of the CF