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ADCY3 — GPR3

Text-mined interactions from Literome

Li et al., J Biol Chem 2010 : Mechanistic investigations have shown that as a G ( i ) -coupled receptor, GPR109A inhibits adenylate cyclase activity upon niacin activation, thereby inhibiting free fatty acid liberation
Li et al., J Biol Chem 2011 : Mechanistic investigations have shown that, upon niacin activation, GPR109A couples to a G(i) protein and inhibits adenylate cyclase activity, leading to inhibition of liberation of free fatty acid
Zhang et al., J Zhejiang Univ Sci B 2012 : Expression of porcine Gpr3 in HEK293 cells resulted in constitutive activation of adenylate cyclase ( AC ) similar in amplitude to that produced by fully stimulated G ( s ) -coupled receptors
Jalink et al., Cell Growth Differ 1993 : LPA stimulates phospholipase C and inhibits adenylate cyclase in its target cells, apparently by activating a specific G-protein coupled receptor