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FOXO4 — MST1

Text-mined interactions from Literome

Lehtinen et al., Cell 2006 : MST1 phosphorylates FOXO proteins at a conserved site within the forkhead domain that disrupts their interaction with 14-3-3 proteins, promotes FOXO nuclear translocation, and thereby induces cell death in neurons
Anand et al., Biochemistry 2008 : We also identify autophosphorylation sites within the MST1 regulatory region and show that both regulatory region phosphorylation and MST1 dimerization contribute to FoxO phosphorylation
Bi et al., J Biol Chem 2010 : We also find the S82A ( serine mutated to alanine ) diminishes MST1 activation and its effect on the FOXO transcription activity