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FAS — LPA

Text-mined interactions from Literome

Meng et al., Gynecol Oncol 2005 (Neoplasm Invasiveness...) : In this study, we observed the effect of lysophosphatidic acid (LPA) on Fas expression and function in ovarian cancer cells ... Our studies suggest that LPA induces translocation of Fas from the cell membrane to the cytosol, which may provide a mechanism by which ovarian cancer cells evade FasL bearing immune cells
Mukherjee et al., J Biol Chem 2012 (Ovarian Neoplasms) : In this study, we demonstrate that lysophosphatidic acid (LPA) , a growth factor-like mediator present at high levels in ascites of ovarian cancer patients, regulates the sterol regulatory element binding protein-FAS and AMP activated protein kinase-ACC pathways in ovarian cancer cells but not in normal or immortalized ovarian epithelial cells