◀ Back to FAS

CAV1 — FAS

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• IRef Biogrid Interaction: FAS — CAV1 (physical association, affinity chromatography technology) Zhang et al., Free Radic Biol Med 2011*
• IRef Dip Interaction: CAV1 — FAS (physical association, anti bait coimmunoprecipitation) Chen et al., Proc Natl Acad Sci U S A 2010*
• IRef Intact Interaction: CAV1 — FAS (physical association, anti bait coimmunoprecipitation) Zhang et al., Free Radic Biol Med 2011*
• IRef Intact Interaction: CAV1 — FAS (colocalization, confocal microscopy) Zhang et al., Free Radic Biol Med 2011*

Text-mined interactions from Literome

Joshi et al., Cancer Res 2008 (Neoplasm Invasiveness...) : Stable expression and knockdown studies of Cav1 in tumor cells showed that phosphorylated Cav1 expression stimulates Rho activation, stabilizes FAK association with FAs , and promotes cell migration and invasion in a ROCK dependent and Src dependent manner
Wu et al., Neurosurgery 2009 (Glioma) : Simvastatin also decreased cholesterol content in lipid raft fractions, suppressed caveolin-1 expression in the lipid rafts, and induced Fas translocation into lipid rafts, suggesting that simvastatin may inhibit the prosurvival PI3K/Akt pathway and trigger caspase-3 dependent apoptotic cell death through the modulation of lipid rafts