◀ Back to EPHB2

EPHB2 — HSPB1

Text-mined interactions from Literome

Minelli et al., Peptides 2006 : It greatly enhances the phosphorylation of hsp27 , alpha-B-crystallin, Cdc2, and p-38 MAPK, whereas it decreases the phosphorylation of MEK1, Cav 2, GSK3a, PKB/Akt, PKCdelta, PKCgamma, and Erk2
Chen et al., Mol Cell Biochem 2010 : ERK1/2 might be involved in HSP27 phosphorylation and migration of VSMCs provoked by AngII and PDGF-BB
Robitaille et al., J Invest Dermatol 2010 (MAP Kinase Signaling System) : The small heat-shock protein Hsp27 undergoes ERK dependent phosphorylation and redistribution to the cytoskeleton in response to dual leucine zipper bearing kinase expression
Shin et al., J Obstet Gynaecol Res 2009 (Pre-Eclampsia) : The interaction between Hsp27 and MAPK was increased, suggesting that phosphorylation of Hsp27 might be induced by p38 and ERK in placentas from patients with pre-eclampsia
Zoubeidi et al., Cancer Res 2010 (MAP Kinase Signaling System...) : Hsp27 overexpression increases IGF-I induced phosphorylation of Erk , p90Rsk, and Akt
Almela et al., J Mol Cell Cardiol 2011 (Morphine Dependence...) : In this study, we investigated Hsp27 and phospho-Hsp27 expression during morphine dependence and withdrawal and evaluated the involvement of ERK in the phosphorylation of Hsp27 in the rat right ventricle ... Pretreatment with SL327, an inhibitor of ERK phosphorylation, decreased activation ( phosphorylation ) of both ERK and Hsp27 ( pERK1 : 4.5±3.6 %, P < 0.0001 ; pERK2 : 42.3±3.3 %, P < 0.0001 ; and pHsp27 : 97.6±1.5 %, P=0.008 ), suggesting that ERK activation triggers Hsp27 phosphorylation