Gene interactions and pathways from curated databases and text-mining

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CD40LG — F3

Pathways - manually collected, often from reviews:

  • OpenBEL Selventa BEL large corpus: F3 → CD40LG (increases)
    Evidence: CD40L also enhances plaque thrombogenicity by decreasing thrombomodulin and inducing TF production in endothelial cells [41,42], SMCs [43,44], and macrophages [45].
  • OpenBEL Selventa BEL large corpus: F3 → CD40LG (increases)
    Evidence: CD40L also promotes enzymatic processes that lead to plaque rupture and thrombosis by inducing macrophage production of MMPs [45,74] and TF [44,45].