Gene interactions and pathways from curated databases and text-mining

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CA1 — MMP2

Text-mined interactions from Literome

Hoffmann et al., Curr Eye Res 2005 : Zymography and ELISA determined the effect of CAI on MMP-2 production of choroidal endothelial cells ( CECs ) stimulated by bFGF and VEGF
Kim et al., J Cell Biochem 2013 (Prostatic Neoplasms) : This suggested that both ROS and Ca(?i) ( 2+ ) signaling play roles in the increased MMP via Ca?(i) ( 2+ ) -dependent and/or -independent mechanisms, since d? ( m ) elevation was reversed by NAC and BAPTA
Kohn et al., J Biol Chem 1994 : This reduction is not due to direct inhibition of the enzyme by CAI or CAI induced MMP-2 degradation ... Cell coincubation with CAI ( 2 microM ) and TGF-beta 1 ( 5 ng/ml ) caused a decrease in the overall amount of latent and activated MMP-2 by zymogram and immunoblot analysis and showed that CAI inhibited TGF-beta 1 stimulation of MMP-2 production at the level of RNA expression