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CA1 — MMP2
Text-mined interactions from Literome
Hoffmann et al., Curr Eye Res 2005
:
Zymography and ELISA determined the
effect of
CAI on
MMP-2 production of choroidal endothelial cells ( CECs ) stimulated by bFGF and VEGF
Kim et al., J Cell Biochem 2013
(Prostatic Neoplasms) :
This suggested that both ROS and
Ca(?i) ( 2+ ) signaling
play roles in the increased
MMP via Ca?(i) ( 2+ ) -dependent and/or -independent mechanisms, since d? ( m ) elevation was reversed by NAC and BAPTA
Kohn et al., J Biol Chem 1994
:
This reduction is not due to direct inhibition of the enzyme by CAI or
CAI induced
MMP-2 degradation ... Cell coincubation with CAI ( 2 microM ) and TGF-beta 1 ( 5 ng/ml ) caused a decrease in the overall amount of latent and activated MMP-2 by zymogram and immunoblot analysis and showed that
CAI inhibited TGF-beta 1 stimulation of
MMP-2 production at the level of RNA expression