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ABL1 — RAF1
Text-mined interactions from Literome
Yu et al., Blood 2003
(Leukemia, Myelogenous, Chronic, BCR-ABL Positive) :
These events were accompanied by down-regulation of the
Raf-1/mitogen induced extracellular kinase ( MEK ) /extracellular signal related kinase ( ERK ) pathway as well as diminished expression of
Bcr/Abl and cyclin D1, cleavage of p21CIP1 and phosphorylation of the retinoblastoma protein ( pRb ), and induction of the stress related kinases Jun kinase (JNK) and p38 mitogen activated protein kinase ( MAPK )
Skorski et al., Cancer Res 1995
(Leukemia, Myelogenous, Chronic, BCR-ABL Positive) :
We show that
c-RAF-1 enzymatic activity is
regulated by
BCR/ABL , although the protein does not associate with BCR/ABL