Gene interactions and pathways from curated databases and text-mining

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ARSA — TNF

Text-mined interactions from Literome

Minuz et al., Br J Pharmacol 2001 : We tested the effects of NCX4016 and ASA on the release of the thromboxane ( TX ) A ( 2 ) metabolite TXB ( 2 ), tumour necrosis factor-alpha (TNF-alpha) , interleukin-6 (IL-6), expression and activity of tissue factor ( TF ) in stimulated, adherent human monocytes
Cai et al., Zhonghua Jie He He Hu Xi Za Zhi 1999 : LPS might activate NF-kappa B in the PIMs, and induce the increase of transcription and expression of TNF-alpha gene ; Both DEX and ASA could inhibit the activation of NF-kappa B and reduce the release of TNF-alpha
Brzozowski et al., J Pharmacol Exp Ther 2004 (Stomach Diseases) : The area of ASA induced gastric lesions, gastric blood flow ( GBF ), expression of mRNA and protein of leptin and plasma leptin, gastrin, interleukin-1beta, and tumor necrosis factor-alpha levels were examined
MacIntyre et al., Int J Immunopharmacol 1991 : Finally, the 5-lipoxygenase inhibitors, ketoconazole and L-656,224, but not the cyclo-oxygenase inhibitor ASA , inhibited TNF stimulated by all agents
Mbodji et al., J Nutr Biochem 2013 (Colitis...) : 5-ASA also reduces mRNA levels of tumor necrosis factor a ( P < .05 )