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ARSA — TNF
Text-mined interactions from Literome
Minuz et al., Br J Pharmacol 2001
:
We tested the
effects of NCX4016 and
ASA on the release of the thromboxane ( TX ) A ( 2 ) metabolite TXB ( 2 ),
tumour necrosis factor-alpha (TNF-alpha) , interleukin-6 (IL-6), expression and activity of tissue factor ( TF ) in stimulated, adherent human monocytes
Cai et al., Zhonghua Jie He He Hu Xi Za Zhi 1999
:
LPS might activate NF-kappa B in the PIMs, and induce the increase of transcription and expression of TNF-alpha gene ; Both DEX and
ASA could inhibit the activation of NF-kappa B and
reduce the release of
TNF-alpha
Brzozowski et al., J Pharmacol Exp Ther 2004
(Stomach Diseases) :
The area of
ASA induced gastric lesions, gastric blood flow ( GBF ), expression of mRNA and protein of leptin and plasma leptin, gastrin, interleukin-1beta, and
tumor necrosis factor-alpha levels were examined
MacIntyre et al., Int J Immunopharmacol 1991
:
Finally, the 5-lipoxygenase inhibitors, ketoconazole and L-656,224, but not the cyclo-oxygenase inhibitor
ASA ,
inhibited TNF stimulated by all agents
Mbodji et al., J Nutr Biochem 2013
(Colitis...) :
5-ASA also
reduces mRNA levels of
tumor necrosis factor a ( P < .05 )