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LIN37 — PSEN2

Text-mined interactions from Literome

Berezovska et al., Brain Res Mol Brain Res 1999 (Alzheimer Disease) : Furthermore, we present evidence demonstrating that there is a functional interaction between PS1 and Notch1 in mammalian neurons, analogous to the sel-12/lin-12 interaction in vulval development in C. elegans [ D. Levitan, T. Doyle, D. Brousseau, M. Lee, G. Thinakaran, H. Slunt, S. Sisodia, I. Greenwald, Assessment of normal and mutant human presenilin function in Caenorhabditis elegans, Proc. Natl. Acad. Sci. U.S.A. 93 ( 1996 ) 14940-14944 ; D. Levitan, I. Greenwald, Effect of Sel-12 presenilin on Lin-12 localization and function in Caenorhabditis elegans, Development, 125 ( 1998 ) 3599-3606 ]
Levitan et al., Development 1998 : Effects of SEL-12 presenilin on LIN-12 localization and function in Caenorhabditis elegans ... We discuss potential parallels for the role of SEL-12/presenilin in facilitating LIN-12/Notch activity and in amyloid precursor protein (APP) processing