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NOTCH1 — PDLIM7
Text-mined interactions from Literome
Cotter et al., J Virol 2000
(Cell Transformation, Viral...) :
Truncated intracellular
NOTCH1 associated with the nuclear membrane ( DeltaE )
transactivates the
LMP1 promoter fivefold ; however, the intranucleus localized form of NOTCH1 ( ICN ) transactivates this promoter approximately twofold in chloroamphenicol acetyltransferase (CAT) reporter assays in BJAB cells ... Similarly, another truncated form of
NOTCH1 , referred to as ICNW, which contains the tryptophan residue W ( 1767 ) within one of the RBP-Jkappa interacting domains,
repressed the
LMP1 promoter approximately twofold
Strobl et al., J Virol 2000
(Burkitt Lymphoma) :
Northern blot analysis revealed that the LMP2A gene is
induced by
Notch-IC in the presence of estrogen, whereas increased expression of
LMP1 could be detected only if cycloheximide was simultaneously added
Gross et al., Int J Cancer 2011
(Burkitt Lymphoma) :
In contrast, NP9 did neither interfere in the activation of the HES1 promoter by
Notch nor the
induction of the viral
LMP1 promoter by EBNA2