Gene interactions and pathways from curated databases and text-mining

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LYN — TNF

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

Text-mined interactions from Literome

Huang et al., J Biol Chem 2003 : c-Src and Lyn , two members of the Src kinase family, were abundantly expressed in A549 cells, and their activation by TNF-alpha or TPA was inhibited by the same inhibitors
Avila et al., Innate Immun 2012 : Analyzing two local MC-dependent innate immune responses in vivo, we found that Lyn positively controls early TNF-a production and immune cell recruitment after an intraperitoneal injection of LPS
Yan et al., J Inflamm 1995 : In fact, only in the presence of Mg2+, but not in the absence of divalent cations or in the presence of Ca2+ alone, TNF increased p58c-fgr and p53/56lyn kinase activities ; and this was prevented by anti-CD18 antibodies