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IL17D — SOCS3

Text-mined interactions from Literome

Owaki et al., J Immunol 2006 : These results suggest that IL-27 inhibits CD28 mediated IL-2 production and also IL-2 responses, and that SOCS3 , whose expression is induced by IL-27 , plays a critical role in the inhibitory effect in a negative feedback mechanism
Schneider et al., Eur J Immunol 2011 : IL-27 induced rapid STAT1 and STAT3 signaling, enhanced STAT1 protein levels, and induced SOCS1 and SOCS3 expression in a STAT1 dependent manner by human CD8 ( + ) T cells