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CREB1 — FGF21
Text-mined interactions from Literome
Azadi et al., Brain Res 2007
(Disease Models, Animal...) :
To shed light on the underlying mechanisms, we studied the effects of 9 days ( starting at postnatal day 2 ) in vitro CNTF+BDNF treatment on the endogenous production of CNTF, BDNF,
fibroblast growth factor 2 (FGF2), or the
activation of extracellular signal regulated kinase ( ERK ), Akt and cAMP-response-element binding protein (
CREB ) in retinal explants
Wu et al., Sci Transl Med 2011
(Diabetes Mellitus, Type 2) :
In brown adipose tissues, both
FGF21 and R1MAb
induced phosphorylation of
CREB ( cyclic adenosine 5'-monophosphate response element binding protein ), and mRNA expression of PGC-1a ( peroxisome proliferator activated receptor-? coactivator 1a ) and the downstream genes associated with oxidative metabolism
Tabernero et al., Mol Cell Neurosci 1998
:
In contrast, neurotrophins, CNTF,
FGF-2 , EGF, and TGF beta
induce little or no phosphorylation of
CREB despite the fact that receptors for these factors are present on Schwann cells