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CCK — SCT
Text-mined interactions from Literome
Lam et al., Life Sci 1999
(Hyperglycemia) :
Secretin significantly ( P < 0.005-P < 0.05 ) increased volume and bicarbonate output and
CCK significantly ( P < 0.01 )
increased the output of bilirubin, pancreatic enzymes, bicarbonate and volume, both during normoglycemia and hyperglycemia ... During hyperglycemia basal,
secretin stimulated and secretin +
CCK stimulated total pancreatico-biliary output were significantly ( P < 0.005-P < 0.05 ) reduced compared to normoglycemia
Katsushima et al., Am J Physiol 1990
:
CCK induced downregulation of VIP and
secretin receptors was associated with the diminished acinar response to VIP or secretin induced adenosine 3',5'-cyclic monophosphate accumulation and amylase secretion, whereas neither Bt2cGMP nor nitroprusside affected VIP induced amylase secretion
Hong et al., Pancreas 1988
(Pancreatitis) :
Intraarterial perfusion of trypsin also inhibited
secretin induced flow and
cholecystokinin evoked enzyme secretion
Nakano et al., Regul Pept 1988
:
Carbachol ( 10 ( -9 ) to 10 ( -6 ) M ), VIP ( 10 ( -9 ) M ),
secretin ( 10 ( -9 ) M ) and glucose ( 11 mM ) did not
stimulate CCK secretion, and the addition of atropine ( 10 ( -5 ) M ) to them led to no significant changes
Schwedes et al., Horm Metab Res 1979
(Acute Disease...) :
SRIF-treatment
diminished insulin,
CCK and the test meal induced increase of
secretin
Johnson et al., Cancer 1981
:
Exogenous gastrin,
secretin , and
CCK increase pancreatic weight DNA, RNA and protein content of the rat pancreas
Jensen et al., Am J Physiol 1983
:
Binding of
125I-secretin was
inhibited by secretin, vasoactive intestinal peptide, PHI, and Gila monster venom but not by glucagon, gastric inhibitory polypeptide,
cholecystokinin , caerulein, gastrin, bovine pancreatic polypeptide, somatostatin, neurotensin, leucine-enkephalin, methionine-enkephalin, carbachol, bombesin, litorin, eledoisin, physalaemin, or substance P
Brodish et al., Pancreas 1994
:
Pancreatic responses to a mixed meal,
cholecystokinin (CCK) dose
response ( 12.5-200 ng/kg/h ), and
secretin dose response ( 16-500 ng/kg/h ) were determined
Tani et al., Biol Pharm Bull 1997
:
Carbachol,
secretin ,
CCK-8 and prostaglandin E2 ( PGE2 ) strongly
stimulated mucin secretion, and gastrin I weakly did
Kitagawa et al., Biomed Pept Proteins Nucleic Acids 1995
:
The maximally stimulated amylase secretion by PACAP27 was not enhanced by VIP or
secretin , but was synergistically
increased by
cholecystokinin and A23187