Gene interactions and pathways from curated databases and text-mining

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AGRP — CCK

Text-mined interactions from Literome

Volkoff et al., Gen Comp Endocrinol 2005 : In goldfish, nutritional status can modify the expression of mRNAs encoding a number of these peptides, which provides further evidence for their roles as appetite regulators : ( 1 ) brain mRNA expression of CCK , CART, tachykinins, galanin, ghrelin, and NPY undergo peri-prandial variations ; and ( 2 ) fasting increases the brain mRNA expression of NPY, AgRP , and ghrelin as well as serum ghrelin levels, and decreases the brain mRNA expression of tachykinins, CART, and CCK
Relling et al., J Anim Sci 2010 (Body Weight) : We conclude that insulin, ghrelin, CCK , and GLP-1 may regulate DMI in sheep by regulating the hypothalamic gene expression of NPY, AgRP , and POMC