Goraya et al., J Biol Chem 2004
(Astrocytoma) :
Regulation of adenylyl cyclases (ACs) by Ca2+ requires capacitative Ca2+ entry ( CCE ) ( Cooper, D. M. F. ( 2003 ) Biochem
Mammen et al., Biochem Biophys Res Commun 2004
(Calcium Signaling...) :
Hippocalcin was predominantly localized to the olfactory cilia, the site of the initial events of olfactory signal transduction, and was found to regulate the activity of ciliary adenylate cyclases (ACs) and particulate guanylyl cyclases (GCs) in a Ca2+ dependent manner
Willoughby et al., J Biol Chem 2005
:
The pH sensitivity of CCE in HEK 293 cells is likely to dampen the effects of pH(i) on Ca2+ regulated ACs and may partly explain the discrepancy between in vitro and in vivo data