Gene interactions and pathways from curated databases and text-mining

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CA2 — CD40LG

Text-mined interactions from Literome

Ho et al., Eur J Pharmacol 1999 : Further investigation of the molecular mechanism demonstrated that tetrandrine inhibited the expression of the protein kinase C-dependent interleukin-2 receptor alpha chain and CD69 but not the expression of the Ca2+ dependent CD40 ligand and CD69
Katsiari et al., Lupus 2002 (Lupus Erythematosus, Systemic) : To explore the regulatory defects underlying the overexpression of CD40 ligand ( CD40L, CD154 ) in human lupus we studied the effects of cyclosporin-A ( CsA ), which blocks Ca2+/calcineurin dependent CD40L gene expression, on peripheral blood derived T cells and monocytes
Jenkins et al., J Cell Sci 1995 : The TRAP induced increase in Ca2+ was reproducible, dose dependent and specific
Schaeffer et al., Biochem Pharmacol 1997 : Thrombin and TRAP also stimulated intracellular Ca2+ increase, monolayer permeability increase, and prostacyclin release in HUVEC