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CAV1 — IRS1

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• IRef Hprd Interaction: CAV1 — IRS1 (in vitro) Panetta et al., Biochem Biophys Res Commun 2004*
• IRef Hprd Interaction: CAV1 — IRS1 (in vivo) Panetta et al., Biochem Biophys Res Commun 2004*

Text-mined interactions from Literome

Salani et al., Endocrinology 2008 : These results demonstrate that : 1 ) Cav-1 down-regulation negatively affects IGF-IR tyrosine phosphorylation ; 2 ) this effect causes a reduced activation of insulin receptor substrate-1 , Shc, and Akt ; and 3 ) Cav-1 is involved in IGF-IR antiapoptotic signaling after serum deprivation
Chen et al., J Cell Physiol 2008 : Regulation of insulin receptor substrate-1 expression levels by caveolin-1