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IL8 — NR0B1
Text-mined interactions from Literome
Araki et al., Oncol Rep 2006
(Colitis) :
DSS induced the weak release of
IL-8 , IL-6, and TGF-beta1
Bhattacharyya et al., Inflamm Bowel Dis 2009
:
DSS induced increases in phospho-IkappaBalpha, nuclear NFkappaB ( p65 ), and
IL-8 secretion in human colonic epithelial cells in tissue culture are attributable to a reactive oxygen species ( ROS ) -induced pathway of inflammation, and do not require TLR4, MyD88, or Bcl10, which are associated with the innate immune pathway of NFkappaB-IL-8 activation ... Data demonstrated that
DSS activates IkappaBalpha, NFkappaB, and
IL-8 through an ROS-Hsp27-IKKbeta mediated pathway, and not through an innate immune cascade
Ozaki et al., Curr Gene Ther 2012
(Body Weight...) :
In addition,
DSS induced expression of tumor necrosis factor-a,
interleukin (IL)-6 , and IL-1ß was significantly decreased