UCSC Genome Browser Gene Interaction Graph

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Gene interactions and pathways from curated databases and text-mining

NPS — VIP

Pathways - manually collected, often from reviews:

Reactome Reaction: VIP → NPS (reaction) Wenzel-Seifert et al., Biochem Pharmacol 2002, Zhang et al., Eur J Pharmacol 2003, Mitsuhashi et al., J Biol Chem 1989, Kozasa et al., Proc Natl Acad Sci U S A 1988, Baker et al., J Biol Chem 1998

Text-mined interactions from Literome

Anand et al., Br J Dermatol 1991 (Dermatitis, Atopic...) : Neuropeptides in skin disease : increased VIP in eczema and psoriasis but not axillary hyperhidrosis
Camilleri et al., Gastroenterology 2010 (Gastrointestinal Diseases...) : NPS-NPSR1 signaling induced increased expression of cholecystokinin, vasoactive intestinal peptide , peptide YY, and somatostatin
Edvinsson et al., Cephalalgia 1995 (Cluster Headache...) : These neuropeptides mediate contraction ( NPY ) and dilation ( VIP , SP, CGRP )
Cai et al., Endocrinology 1997 : Regulation of Interleukin-6 (IL-6) production in bone marrow ( BM ) -derived stromal cells by neuropeptides , pituitary adenylate cyclase activating polypeptide ( PACAP ) and vasoactive intestinal peptide (VIP) , was examined