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CD4 — STAT3
Text-mined interactions from Literome
Kitamura et al., Immunity 2005
:
Thus,
IL-6-STAT3 mediated increase of cathepsin S activity reduces the MHCII alphabeta dimer, Ii, and H2-DM levels in DCs, and
suppresses CD4 ( + ) T cell mediated immune responses
Wang et al., Cell Immunol 2007
:
The role of
STAT3 in antigen-IgG
inducing regulatory
CD4 ( + ) Foxp3 ( + ) T cells
Rafei et al., J Immunol 2009
(Encephalomyelitis, Autoimmune, Experimental) :
In an effort to decipher MSC mode of action, we found that MSC conditioned medium
inhibits EAE derived
CD4 T cell activation by suppressing
STAT3 phosphorylation via MSC derived CCL2
Alam et al., Proc Natl Acad Sci U S A 2010
(Hepatitis, Animal) :
Notch mediated stimulation of
CD4 ( + ) T cells
increased the production of IL-22 even in the absence of
STAT3
Manuel et al., Cancer Res 2011
(Melanoma, Experimental) :
In vaccinated mice, silencing
STAT3 increased the proliferation and granzyme B levels of intratumoral
CD4 ( + ) and CD8 ( + ) T cells