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PDK4 — PPARGC1A

Text-mined interactions from Literome

Ma et al., J Biol Chem 2005 : We have found that PGC-1alpha will induce the expression of both the PDK2 and PDK4 genes in primary rat hepatocytes and ventricular myocytes ... Although HNF4 and PGC-1alpha interact to stimulate several genes encoding gluconeogenic enzymes, the induction of PDK4 does not involve interactions of PGC-1alpha with HNF4
Wende et al., Mol Cell Biol 2005 : PGC-1alpha mediated activation of PDK4 expression was shown to occur at the transcriptional level and was mapped to a putative nuclear receptor binding site ... As predicted by the effects of PGC-1alpha on PDK4 gene transcription, overexpression of PGC-1alpha in C ( 2 ) C ( 12 ) myotubes decreased glucose oxidation rates