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CX3CL1 — MAPK3
Text-mined interactions from Literome
Brand et al., Gastroenterology 2002
(MAP Kinase Signaling System...) :
Fractalkine mediated the MEK-1 and G alpha i-dependent but phosphatidylinositol-3-kinase independent activation of extracellular signal regulated
kinase-MAPK
Vomaske et al., PLoS Pathog 2009
:
While US28 binding of both RANTES and
Fractalkine activate FAK and
ERK-1/2 , RANTES signals through Galpha12 and Fractalkine through Galphaq
Ralay Ranaivo et al., Brain Res 2010
(MAP Kinase Signaling System) :
Albumin activated ERK1/2, p38
MAPK and JNK signaling pathways in astrocytes, and
induced the production of interleukin (IL)-1beta, inducible nitric oxide (NO) synthase, the NO metabolite nitrite, and the chemokine
CX3CL1 while reducing the level of S100B
Corcione et al., PloS one 2009
:
CX(3)CL1 signalling in germinal centre B cells
involved PI3K,
Erk1/2 , p38, and Src phosphorylation, as assessed by Western blot experiments
Clements et al., J Immunol 2010
(Angiomyolipoma...) :
In AML cells, their ligands CXCL12
CX3CL1 , CCL11, CCL24, and CCL28
caused robust phosphorylation of p42/44
MAPK and Akt
Ferretti et al., Leukemia 2011
(Leukemia, Lymphocytic, Chronic, B-Cell) :
CX(3)CL1 induced phosphorylation of PI3K,
Erk1/2 , p38, Akt and Src was involved in induction of CLL chemotaxis
Park et al., Transplant Proc 2012
(MAP Kinase Signaling System) :
Fractalkine ( 50 ng/mL ) also
induced cellular ROS production and activation of ERK1/2 and p38
MAPK in mesangial cells
Gan et al., Cell Tissue Res 2013
(Inflammation) :
Inhibitors of
p38MAPK , JAK-STAT, NF-kB, and AP-1 significantly
reduced CX3CL1 and CX3CR1 expression