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CASP8 — TNFSF12
Pathways - manually collected, often from reviews:
Text-mined interactions from Literome
Abend et al., J Virol 2010
:
In a KS tumor derived endothelial cell line, the downregulation of TWEAKR by miR-K10a resulted in reduced levels of
TWEAK induced
caspase activation
Ikner et al., J Biol Chem 2011
:
Knockdown of RIP1 by siRNA prevented
TWEAK induced association of FADD with
caspase-8 but not formation of the FN14-TRAF2-cIAP1 complex and inhibited apoptosis activation