Hosoi et al., Eur J Pharmacol 2007
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Inhibitory effect of 4- ( 2-aminoethyl ) -benzenesulfonyl fluoride, a serine protease inhibitor, on PI3K inhibitor induced CHOP expression
Mantuano et al., J Neurosci 2011
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In cultured SCs, the PKR-like ER kinase target eIF2a was phosphorylated and CHOP was induced by ( 1 ) inhibiting PI3K , ( 2 ) treating the cells with tumor necrosis factor-a (TNF-a), or ( 3 ) genetic silencing of LRP1