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AKT1 — MME
Text-mined interactions from Literome
Sumitomo et al., Cancer Res 2001
(Prostatic Neoplasms) :
Recombinant
NEP and induced NEP expression in TSU-Pr1 cells using a tetracycline-repressive expression system
inhibited ET-1 mediated phosphorylation of IGF-IRbeta and
Akt , and blocked the protective effects of ET-1 against apoptosis induced by serum starvation
Osman et al., Cancer 2006
(Disease Progression...) :
Loss of
neutral endopeptidase and
activation of
protein kinase B ( Akt ) is associated with prostate cancer progression ... The results indicated that the induction of
NEP expression inhibited established xenograft tumor growth,
diminished Akt phosphorylation, and increased PTEN protein levels