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AKT1 — DST

Text-mined interactions from Literome

Jenkins et al., Environ Health Perspect 2011 (Cell Transformation, Neoplastic...) : At the molecular level, 25 µg BPA/L, but not 2,500 µg BPA/L , increased phosphorylation of erbB2, erbB3, insulin-like growth factor 1 receptor, and Akt in the mammary gland
Ptak et al., Toxicol Lett 2012 (MAP Kinase Signaling System...) : Similarly to leptin, but with different kinetics and duration, BPA induced phosphorylation of Stat3, ERK1/2 and Akt
Bulzomi et al., IUBMB Life 2012 : The molecular pathways involved require p38 activation, whereas, the BPA induced AKT activation is completely prevented by the Nar treatment
Kang et al., Food Chem Toxicol 2013 (Ovarian Neoplasms) : In parallel with its mRNA level, the protein expression of ERa was induced, and phosphorylated insulin receptor substrate-1 ( p-IRS-1 ), phosphorylated Akt1/2/3 , and cyclin D1 were increased by BPA or E2