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AKT1 — CCL4

Text-mined interactions from Literome

Majka et al., Stem Cells 2000 : In contrast, the CCR5 ligands ( macrophage inflammatory protein-1alpha [ MIP-1alpha ], MIP-1beta , and RANTES ) did not activate calcium flux, MAPK and AKT phosphorylation or chemotaxis of CD34 ( + ) KIT ( + ) cells or cells isolated from the BFU-E colonies
Vroon et al., J Leukoc Biol 2004 (Calcium Signaling) : Moreover, the calcium response and phosphorylation of protein kinase B and extracellular regulated kinase in response to CCL4 were significantly increased in GRK2+/- T cells, showing that signaling is increased when the level of GRK2 is reduced
Knieke et al., PloS one 2012 : In the presence of CD152 signaling, the chemoattractant CCL4 selectively induces the full activation of Akt via phosphorylation at threonine 308 and serine 473 in pro-inflammatory Th lymphocytes expressing the cognate chemokine receptor CCR5