Pathways - manually collected, often from reviews:
OpenBEL Selventa BEL large corpus:
MEF2A
→
MAPK14
(directlyIncreases, MAPK14 Activity, MEF2A Activity)
Zhao et al., Mol Cell Biol 1999 Evidence: These data support the idea that p38 is the enzyme downstream of MKK6 in vivo that mediates MKK6-induced MEF2A activation.
OpenBEL Selventa BEL large corpus:
MEF2A
→
MAPK14
(directlyIncreases, MAPK14 Activity, MEF2A Activity)
Zhao et al., Mol Cell Biol 1999 Evidence: We found that MEF2A, but not MEF2B or MEF2D, is a substrate for p38. Among the four p38 group members, p38 is the most potent kinase for MEF2A. Threonines 312 and 319 within the transcription activation domain of MEF2A are the regulatory sites phosphorylated by p38.
OpenBEL Selventa BEL large corpus:
MEF2A
→
MAPK14
(directlyIncreases, MAPK14 Activity, MEF2A Activity)
Zhao et al., Mol Cell Biol 1999 Evidence: We showed previously that the transactivation activity of MEF2C is stimulated by p38 mitogen-activated protein (MAP) kinase. In this study, we examined the potential role of the p38 MAP kinase pathway in regulating the other MEF2 family members. We found that MEF2A, but not MEF2B or MEF2D, is a substrate for p38. Among the four p38 group members, p38 is the most potent kinase for MEF2A. Threonines 312 and 319 within the transcription activation domain of MEF2A are the regulatory sites phosphoryl...
OpenBEL Selventa BEL large corpus:
MEF2A
→
MAPK14
(directlyIncreases, MEF2A Activity)
Zhao et al., Mol Cell Biol 1999 Evidence: We found that MEF2A, but not MEF2B or MEF2D, is a substrate for p38. Among the four p38 group members, p38 is the most potent kinase for MEF2A. Threonines 312 and 319 within the transcription activation domain of MEF2A are the regulatory sites phosphorylated by p38.
OpenBEL Selventa BEL large corpus:
MEF2A
→
MAPK14
(directlyIncreases, MEF2A Activity)
Zhao et al., Mol Cell Biol 1999 Evidence: We showed previously that the transactivation activity of MEF2C is stimulated by p38 mitogen-activated protein (MAP) kinase. In this study, we examined the potential role of the p38 MAP kinase pathway in regulating the other MEF2 family members. We found that MEF2A, but not MEF2B or MEF2D, is a substrate for p38. Among the four p38 group members, p38 is the most potent kinase for MEF2A. Threonines 312 and 319 within the transcription activation domain of MEF2A are the regulatory sites phosphoryl...