Ashizawa et al., Int J Oncol 2011
(Lymphoma) :
Notably, Tyr-705 phosphorylated STAT3 up-regulation was not significantly suppressed by STX-0119 , as opposed to other STAT3 inhibitors
Ashizawa et al., Int J Oncol 2013
:
STX-0119 , an inhibitor of STAT3 , may serve as a novel therapeutic compound against GBM-SCs even in temozolomide-resistant GBM patients and has the potential for GBM-SC-specific therapeutics in combination with temozolomide plus radiation therapy