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MLST8 — NF2
Text-mined interactions from Literome
James et al., Mol Cell Biol 2009
(Meningioma...) :
Merlin does not
regulate mTORC1 via the established mechanism of phosphoinositide 3-kinase-Akt or mitogen activated protein kinase/extracellular signal regulated kinase mediated TSC2 inactivation and may instead regulate TSC/mTOR signaling in a novel fashion
López-Lago et al., Mol Cell Biol 2009
(Mesothelioma) :
Loss of the tumor suppressor gene
NF2 , encoding merlin, constitutively
activates integrin dependent
mTORC1 signaling