Gene interactions and pathways from curated databases and text-mining

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ARC — MED23

Text-mined interactions from Literome

Guzowski et al., J Neurosci 2001 : Arc RNA expression differed from that of zif268 and c-fos in two regards : ( 1 ) hippocampal Arc RNA levels were correlated with learning of the hippocampal dependent spatial, but not hippocampal independent cued response, water task, and ( 2 ) Arc RNA levels in the hippocampus and entorhinal cortex increased after spatial reversal learning relative to an asymptotic performance group
Fujimoto et al., J Neurosci Res 2004 (Seizures) : We found that the overexpression of Arc as well as Arc induction by seizure in vivo decreased microtubule associated protein 2 (MAP2) staining in the dendrites by immunocytochemistry, although MAP2 content was not changed on Western blot
Holloway-Erickson et al., Frontiers in behavioral neuroscience 2012 : Memory modulating BLA manipulations influence expression of the protein product of the immediate early gene activity regulated cytoskeletal associated protein ( Arc ) in the dorsal hippocampus, and hippocampal expression of Arc protein is critically involved in memory consolidation and long-term potentiation