◀ Back to MAPK3

MAPK3 — TREM2

Text-mined interactions from Literome

Watarai et al., Proc Natl Acad Sci U S A 2008 : However, when coupled with Sema6D, a ligand for Plexin-A1, limited TLR-stimulation resulted in PDC-TREM mediated DAP12 dependent phosphorylation of phosphoinositide 3-kinase (PI3K) and extracellular regulated kinase (Erk) 1/2 at 6-9 h, and IFN-alpha was produced
Peng et al., Science signaling 2010 : Here, we demonstrate that the ligation of TREM2 activated phosphatidylinositol 3-kinase (PI3K), extracellular signal regulated kinase 1 ( ERK1 ) and ERK2, and the guanine nucleotide exchange factor Vav3 ; induced the mobilization of intracellular calcium ( Ca ( 2+ ) ) and the reorganization of actin ; and prevented apoptosis