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SOS1 — STAT3

Pathways - manually collected, often from reviews:

• NCI Pathway Database IL6-mediated signaling events: STAT3 (dimer)/FOXO1 complex (STAT3-FOXO1) → GRB2/SOS1/GAB family/SHP2 complex (GRB2-SOS1-GAB1_GAB2-PTPN11) (transcription, activates)
  Kortylewski et al., J Biol Chem 2003, Wegenka et al., Mol Cell Biol 1993, Schaper et al., Biochem J 1998
  Evidence: mutant phenotype, reporter gene, physical interaction, other species