Gene interactions and pathways from curated databases and text-mining

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AP2M1 — GAK

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

Text-mined interactions from Literome

Lee et al., J Cell Sci 2005 : Surprisingly, while clathrin depletion does not prevent adaptors from assembling on the membrane, depletion of GAK caused a dramatic reduction in AP2 and epsin on the plasma membrane and AP1 and GGA at the trans-Golgi network
Neveu et al., PLoS Pathog 2012 (Hepatitis C) : Furthermore, AAK1 and GAK , serine/threonine kinases known to stimulate binding of AP2M1 to host cargo proteins, regulate core-AP2M1 binding and are essential for HCV assembly