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AP2M1 — GAK
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *
Text-mined interactions from Literome
Lee et al., J Cell Sci 2005
:
Surprisingly, while clathrin depletion does not prevent adaptors from assembling on the membrane, depletion of
GAK caused a dramatic reduction in
AP2 and epsin on the plasma membrane and AP1 and GGA at the trans-Golgi network
Neveu et al., PLoS Pathog 2012
(Hepatitis C) :
Furthermore, AAK1 and
GAK , serine/threonine kinases known to stimulate binding of AP2M1 to host cargo proteins,
regulate core-AP2M1 binding and are essential for HCV assembly