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TNFalpha → LPS: " Hence, we hypothesized that the actin cytoskeleton is integral to adherence induced priming for enhanced LPS induced TNFalpha production "
TNFalpha → LPS: " In contrast to nonadherent cells, LPS induced significant transcription of TNFalpha mRNA and production of TNFalpha in adherent monocytes "
TNFalpha → LPS: " Disrupting the actin cytoskeleton with cytochalasin D ( CD ) in adherent monocytes inhibited LPS induced TNFalpha production by 55 %, thereby abrogating adherence induced priming "
ERK 1/2 ⊣ LPS: " Moreover, CD pretreatment abrogated adherence induced activation of Pyk2, a major focal adhesion kinase, and ERK 1/2 , a component of the mitogen activated protein kinase ( MAPK ) signaling pathway, and it completely inhibited LPS induced ERK 1/2 activation "
ERK 1/2 ⊣ ERK 1/2: " Moreover, CD pretreatment abrogated adherence induced activation of Pyk2, a major focal adhesion kinase, and ERK 1/2 , a component of the mitogen activated protein kinase ( MAPK ) signaling pathway, and it completely inhibited LPS induced ERK 1/2 activation "
ERK 1/2 ⊣ Pyk2: " Moreover, CD pretreatment abrogated adherence induced activation of Pyk2 , a major focal adhesion kinase, and ERK 1/2, a component of the mitogen activated protein kinase ( MAPK ) signaling pathway, and it completely inhibited LPS induced ERK 1/2 activation "
ERK 1/2 ⊣ LPS: " Moreover, CD pretreatment abrogated adherence induced activation of Pyk2, a major focal adhesion kinase, and ERK 1/2 , a component of the mitogen activated protein kinase ( MAPK ) signaling pathway, and it completely inhibited LPS induced ERK 1/2 activation "
ERK 1/2 ⊣ Pyk2: " Moreover, CD pretreatment abrogated adherence induced activation of Pyk2 , a major focal adhesion kinase, and ERK 1/2, a component of the mitogen activated protein kinase ( MAPK ) signaling pathway, and it completely inhibited LPS induced ERK 1/2 activation "
Pyk2 ⊣ LPS: " Moreover, CD pretreatment abrogated adherence induced activation of Pyk2 , a major focal adhesion kinase, and ERK 1/2, a component of the mitogen activated protein kinase ( MAPK ) signaling pathway, and it completely inhibited LPS induced ERK 1/2 activation "