ID:Q059Y4_MOUSE DESCRIPTION: RecName: Full=Protein Wnt; FUNCTION: Ligand for members of the frizzled family of seven transmembrane receptors (By similarity). SUBCELLULAR LOCATION: Secreted, extracellular space, extracellular matrix (By similarity). SIMILARITY: Belongs to the Wnt family.
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on Q059Y4
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Gene Ontology (GO) Annotations with Structured Vocabulary
Molecular Function: GO:0005096 GTPase activator activity GO:0005102 receptor binding GO:0030295 protein kinase activator activity GO:0044212 transcription regulatory region DNA binding
Biological Process: GO:0006468 protein phosphorylation GO:0007275 multicellular organism development GO:0010628 positive regulation of gene expression GO:0016055 Wnt signaling pathway GO:0030154 cell differentiation GO:0030308 negative regulation of cell growth GO:0030325 adrenal gland development GO:0030335 positive regulation of cell migration GO:0030336 negative regulation of cell migration GO:0031667 response to nutrient levels GO:0032147 activation of protein kinase activity GO:0034394 protein localization to cell surface GO:0043066 negative regulation of apoptotic process GO:0043547 positive regulation of GTPase activity GO:0045892 negative regulation of transcription, DNA-templated GO:0045893 positive regulation of transcription, DNA-templated GO:0048706 embryonic skeletal system development GO:0051496 positive regulation of stress fiber assembly GO:0060197 cloacal septation GO:0060484 lung-associated mesenchyme development GO:0060548 negative regulation of cell death GO:0060675 ureteric bud morphogenesis GO:0061101 neuroendocrine cell differentiation GO:0072177 mesonephric duct development GO:0090037 positive regulation of protein kinase C signaling GO:0090090 negative regulation of canonical Wnt signaling pathway