ID:PEX3_MOUSE DESCRIPTION: RecName: Full=Peroxisomal biogenesis factor 3; AltName: Full=Peroxin-3; AltName: Full=Peroxisomal assembly protein PEX3; FUNCTION: Involved in peroxisome biosynthesis and integrity. Assembles membrane vesicles before the matrix proteins are translocated. As a docking factor for PEX19, is necessary for the import of peroxisomal membrane proteins in the peroxisomes. SUBUNIT: Interacts with PEX19 (By similarity). SUBCELLULAR LOCATION: Peroxisome membrane; Multi-pass membrane protein. TISSUE SPECIFICITY: Identified in all tissues analyzed, with the strongest expression in liver and in testis. SIMILARITY: Belongs to the peroxin-3 family.
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on Q9QXY9
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
KEGG - Kyoto Encyclopedia of Genes and Genomes mmu04146 - Peroxisome
Reactome (by CSHL, EBI, and GO)
Protein Q9QXY9 (Reactome details) participates in the following event(s):
R-MMU-382613 PEX-19 docks ABCD1/D2/D3 to peroximal membrane R-MMU-1369062 ABC transporters in lipid homeostasis R-MMU-382556 ABC-family proteins mediated transport R-MMU-382551 Transport of small molecules