ID:SCMC3_MOUSE DESCRIPTION: RecName: Full=Calcium-binding mitochondrial carrier protein SCaMC-3; AltName: Full=Small calcium-binding mitochondrial carrier protein 3; AltName: Full=Solute carrier family 25 member 23; FUNCTION: Calcium-dependent mitochondrial solute carrier. Mitochondrial solute carriers shuttle metabolites, nucleotides, and cofactors through the mitochondrial inner membrane. May act as a ATP-Mg/Pi exchanger that mediates the transport of Mg-ATP in exchange for phosphate, catalyzing the net uptake or efflux of adenine nucleotides into or from the mitochondria (By similarity). SUBCELLULAR LOCATION: Mitochondrion inner membrane; Multi-pass membrane protein (By similarity). SIMILARITY: Belongs to the mitochondrial carrier family. SIMILARITY: Contains 3 EF-hand domains. SIMILARITY: Contains 3 Solcar repeats.
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on Q6GQS1
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Gene Ontology (GO) Annotations with Structured Vocabulary
Molecular Function: GO:0005347 ATP transmembrane transporter activity GO:0005509 calcium ion binding GO:0015217 ADP transmembrane transporter activity GO:0046872 metal ion binding
Biological Process: GO:0002082 regulation of oxidative phosphorylation GO:0006839 mitochondrial transport GO:0006851 mitochondrial calcium ion transport GO:0015866 ADP transport GO:0015867 ATP transport GO:0036444 mitochondrial calcium uptake GO:0043457 regulation of cellular respiration GO:0051282 regulation of sequestering of calcium ion GO:0051503 adenine nucleotide transport GO:0055085 transmembrane transport GO:0071277 cellular response to calcium ion GO:0097274 urea homeostasis