Human Gene REEP4 (uc003xau.1)
Description: Homo sapiens receptor accessory protein 4 (REEP4), mRNA.
Transcript (Including UTRs)
Position: hg19 chr8:21,995,533-21,999,448 Size: 3,916 Total Exon Count: 8 Strand: -
Coding Region
Position: hg19 chr8:21,996,000-21,998,995 Size: 2,996 Coding Exon Count: 8
Data last updated at UCSC: 2013-06-14
Sequence and Links to Tools and Databases
Comments and Description Text from UniProtKB
ID: REEP4_HUMAN
DESCRIPTION: RecName: Full=Receptor expression-enhancing protein 4;
FUNCTION: May enhance the cell surface expression of odorant receptors (By similarity).SUBUNIT: Interacts with odorant receptor proteins (By similarity).SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein (By similarity).SIMILARITY: Belongs to the DP1 family.
Primer design for this transcript
Comparative Toxicogenomics Database (CTD)
Common Gene Haplotype Alleles
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RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
Microarray Expression Data
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mRNA Secondary Structure of 3' and 5' UTRs
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Protein Domain and Structure Information
InterPro Domains: Graphical view of domain structure IPR004345 - TB2_DP1_HVA22
Pfam Domains: PF03134 - TB2/DP1, HVA22 family
ModBase Predicted Comparative 3D Structure on Q9H6H4
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Gene Ontology (GO) Annotations with Structured Vocabulary
Descriptions from all associated GenBank mRNAs
LF210148 - JP 2014500723-A/17651: Polycomb-Associated Non-Coding RNAs.AK025930 - Homo sapiens cDNA: FLJ22277 fis, clone HRC03740.AF218014 - Homo sapiens clone PP432 unknown mRNA.BC050622 - Homo sapiens receptor accessory protein 4, mRNA (cDNA clone MGC:60090 IMAGE:6504298), complete cds.BC013048 - Homo sapiens receptor accessory protein 4, mRNA (cDNA clone MGC:9377 IMAGE:3863838), complete cds.LF335126 - JP 2014500723-A/142629: Polycomb-Associated Non-Coding RNAs.JD058159 - Sequence 39183 from Patent EP1572962.AK172846 - Homo sapiens cDNA FLJ24007 fis, clone KAT02841.AK025899 - Homo sapiens cDNA: FLJ22246 fis, clone HRC02637.JD361953 - Sequence 342977 from Patent EP1572962.JD076691 - Sequence 57715 from Patent EP1572962.JD364827 - Sequence 345851 from Patent EP1572962.JD477349 - Sequence 458373 from Patent EP1572962.JD526803 - Sequence 507827 from Patent EP1572962.JD257736 - Sequence 238760 from Patent EP1572962.AY562242 - Homo sapiens receptor expression enhancing protein 4 (REEP4) mRNA, complete cds.JF432791 - Synthetic construct Homo sapiens clone IMAGE:100074038 receptor accessory protein 4 (REEP4) gene, encodes complete protein.KJ894819 - Synthetic construct Homo sapiens clone ccsbBroadEn_04213 REEP4 gene, encodes complete protein.CR457353 - Homo sapiens full open reading frame cDNA clone RZPDo834C0810D for gene FLJ22246, hypothetical protein FLJ22246; complete cds, incl. stopcodon.LF335125 - JP 2014500723-A/142628: Polycomb-Associated Non-Coding RNAs.LF335124 - JP 2014500723-A/142627: Polycomb-Associated Non-Coding RNAs.AK302352 - Homo sapiens cDNA FLJ56749 complete cds, highly similar to Receptor expression-enhancing protein 4.LF335121 - JP 2014500723-A/142624: Polycomb-Associated Non-Coding RNAs.JD025097 - Sequence 6121 from Patent EP1572962.JD227381 - Sequence 208405 from Patent EP1572962.JD439129 - Sequence 420153 from Patent EP1572962.JD336600 - Sequence 317624 from Patent EP1572962.MA445725 - JP 2018138019-A/17651: Polycomb-Associated Non-Coding RNAs.MA570703 - JP 2018138019-A/142629: Polycomb-Associated Non-Coding RNAs.MA570702 - JP 2018138019-A/142628: Polycomb-Associated Non-Coding RNAs.MA570701 - JP 2018138019-A/142627: Polycomb-Associated Non-Coding RNAs.MA570698 - JP 2018138019-A/142624: Polycomb-Associated Non-Coding RNAs.
Other Names for This Gene
Alternate Gene Symbols: C8orf20, D3DSQ9, NM_025232, NP_079508, PP432, Q86VL1, Q9H6H4, Q9H6I5, Q9HBP4, REEP4_HUMANUCSC ID: uc003xau.1RefSeq Accession: NM_025232
Protein: Q9H6H4
(aka REEP4_HUMAN)
CCDS: CCDS6024.1
Gene Model Information
category:
coding
nonsense-mediated-decay:
no
RNA accession:
NM_025232.2
exon count:
8 CDS single in 3' UTR:
no
RNA size:
1731
ORF size:
774 CDS single in intron:
no
Alignment % ID:
100.00
txCdsPredict score:
1748.00 frame shift in genome:
no
% Coverage:
97.86
has start codon:
yes
stop codon in genome:
no
# of Alignments:
1
has end codon:
yes
retained intron:
no
# AT/AC introns
0
selenocysteine:
no
end bleed into intron:
0 # strange splices:
0
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Methods, Credits, and Use Restrictions
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