Human Gene DLGAP2 (uc003wpj.2)
  Description: Homo sapiens ERICH1 antisense RNA 1 (DLGAP2), non-coding RNA.
Transcript (Including UTRs)
   Position: hg19 chr8:687,587-1,087,777 Size: 400,191 Total Exon Count: 4 Strand: +
Coding Region
   Position: hg19 chr8:772,179-1,087,483 Size: 315,305 Coding Exon Count: 3 

Page IndexSequence and LinksUniProtKB CommentsPrimersGenetic AssociationsMalaCards
CTDGene AllelesRNA-Seq ExpressionMicroarray ExpressionRNA StructureProtein Structure
Other SpeciesmRNA DescriptionsOther NamesModel InformationMethods
Data last updated at UCSC: 2013-06-14

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr8:687,587-1,087,777)mRNA (may differ from genome)Protein (84 aa)
Gene SorterGenome BrowserOther Species FASTAGene interactionsTable SchemaAlphaFold
BioGPSEnsemblExonPrimerGeneCardsH-INVHGNC
Human Cortex Gene ExpressionLynxMalacardsMGIneXtProtPubMed
UniProtKB

-  Comments and Description Text from UniProtKB
  ID: ERAS1_HUMAN
DESCRIPTION: RecName: Full=Putative uncharacterized protein encoded by ERICH1-AS1; AltName: Full=ERICH1 antisense RNA 1; AltName: Full=ERICH1 antisense gene protein 1; AltName: Full=Putative DAP-2 like protein;
CAUTION: Could be the product of a pseudogene.

-  Primer design for this transcript
 

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3


-  Genetic Association Studies of Complex Diseases and Disorders
  Genetic Association Database (archive): DLGAP2
CDC HuGE Published Literature: DLGAP2
Positive Disease Associations: Iron , Triglycerides
Related Studies:
  1. Iron
    , , . [PubMed 0]
  2. Triglycerides
    , , . [PubMed 0]

-  MalaCards Disease Associations
  MalaCards Gene Search: DLGAP2
Diseases sorted by gene-association score: ceroid lipofuscinosis, neuronal, 8, northern epilepsy variant (7)

-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene           more ... click here to view the complete list

+  Common Gene Haplotype Alleles
  Press "+" in the title bar above to open this section.

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 3.17 RPKM in Testis
Total median expression: 4.24 RPKM



View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
  Press "+" in the title bar above to open this section.

-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -162.50326-0.498 Picture PostScript Text
3' UTR -57.14294-0.194 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  ModBase Predicted Comparative 3D Structure on P0C838
FrontTopSide
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologGenome BrowserNo orthologNo orthologNo orthologNo ortholog
Gene DetailsGene Details    
Gene SorterGene Sorter    
 RGD    
 Protein Sequence    
 Alignment    

-  Descriptions from all associated GenBank mRNAs
  BC022082 - Homo sapiens cDNA clone IMAGE:4824304.
KJ904324 - Synthetic construct Homo sapiens clone ccsbBroadEn_13718 C8orf68 gene, encodes complete protein.
BC038783 - Homo sapiens chromosome 8 open reading frame 68, mRNA (cDNA clone IMAGE:5271578).

-  Other Names for This Gene
  Alternate Gene Symbols: C8orf68, ERAS1_HUMAN, ERICH1-AS1, NR_073397, P0C838, uc003wpj.1
UCSC ID: uc003wpj.2
RefSeq Accession: NR_073466
Protein: P0C838 (aka ERAS1_HUMAN)

-  Gene Model Information
 
category: coding nonsense-mediated-decay: no RNA accession: NR_073397.1
exon count: 4CDS single in 3' UTR: no RNA size: 872
ORF size: 255CDS single in intron: no Alignment % ID: 100.00
txCdsPredict score: 629.00frame shift in genome: no % Coverage: 98.28
has start codon: yes stop codon in genome: no # of Alignments: 1
has end codon: yes retained intron: no # AT/AC introns 0
selenocysteine: no end bleed into intron: 0# strange splices: 0
Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.