Schema for Layered H3K27Ac - H3K27Ac Mark (Often Found Near Regulatory Elements) on 7 cell lines from ENCODE
  Database: hg38    Primary Table: wgEncodeBroadHistoneGm12878H3k27acStdSig    Row Count: 1   Data last updated: 2014-12-09
On download server: MariaDB table dump directory
fieldexampleSQL type info
fileName /gbdb/hg38/bbi/wgEncodeReg/...varchar(255) values

Sample Rows
 
fileName
/gbdb/hg38/bbi/wgEncodeReg/wgEncodeRegMarkH3k27ac/wgEncodeBroadHistoneGm12878H3k27acStdSig.bigWig

Note: all start coordinates in our database are 0-based, not 1-based. See explanation here.

Layered H3K27Ac (wgEncodeRegMarkH3k27ac) Track Description
 

Description

Chemical modifications (e.g., methylation and acetylation) to the histone proteins present in chromatin influence gene expression by changing how accessible the chromatin is to transcription. A specific modification of a specific histone protein is called a histone mark. This track shows the levels of enrichment of the H3K27Ac histone mark across the genome as determined by a ChIP-seq assay. The H3K27Ac histone mark is the acetylation of lysine 27 of the H3 histone protein, and it is thought to enhance transcription possibly by blocking the spread of the repressive histone mark H3K27Me3. Additional histone marks and other chromatin associated ChIP-seq data is available at the Broad Histone page.

Display Conventions and Configuration

By default, this track uses a transparent overlay method of displaying data from a number of cell lines in the same vertical space. Each of the cell lines in this track is associated with a particular color, and these colors are relatively light and saturated so as to work best with the transparent overlay. The color of these tracks match their versions from their lifted source on the hg19 assembly. The colors are consistent with the other hg19 lifted tracks located in the ENCODE Regulation supertrack, with the exception being the DNase tracks, as they were not lifted from hg19 and are colored to reflect similarity of cell types.

Credits

This track shows data from the Bernstein Lab at the Broad Institute, as part of the ENCODE Consortium.

Data Release Policy

Primary ENCODE data produced during the 2007-2012 production phase were subject to a restriction period. However, the data here are past those restrictions and are freely available. The full data release policy for ENCODE is available here.