Pathways - manually collected, often from reviews:
OpenBEL Selventa BEL large corpus:
HIF1A
→
ZNF197
(decreases, ZNF197 Activity, HIF1A Activity)
Li et al., EMBO J 2003* Evidence: Taken together, our experiments suggest that the VHLaK protein and pVHL repress HIF-1a transactivation and that pVHL-mediated recruitment of VHLaK to HIF-1a is required for the transcriptional repression......These results suggest that VHLaK participates in the down-regulation of VEGF expression and that this activity requires the presence of the wild-type pVHL.
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *