Gene interactions and pathways from curated databases and text-mining

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MAPK14 — YWHAB

Text-mined interactions from Literome

Trakul et al., J Biol Chem 2005 (MAP Kinase Signaling System) : Because c-Raf-1 and B-Raf are both required for maximal MAPK stimulation by epidermal growth factor in neuronal and epithelial cell lines, we determined whether RKIP significantly affects MAPK signaling
Burger et al., Eur Urol 2006 (Microsatellite Instability...) : The present study investigated B-RAF mutations, MSI status, and activation of MAPK signaling in prostate tumors
Yue et al., Oncogene 2006 : No changes in the activity of B-Raf were detectable during progesterone induced oocyte maturation, after egg fertilization, or during the early embryonic cell cycle, arguing against a role for B-Raf in the mitotic activation of MEK1 and p42 MAPK ... We found that both B-Raf and C-Raf, but not Mos, are required for Ras induced MEK1 and p42 MAPK activation
Hao et al., Mol Cancer Ther 2007 (Colorectal Neoplasms...) : These observations suggest that inhibition of B-Raf activation of mitogen activated protein kinase ( MAPK ) /extracellular signal regulated kinase kinase ( MEK ) and the extracellular signal regulated kinase MAPK cascade may be an effective approach for the treatment of RAS and B-RAF mutation positive melanomas and colon carcinomas
Denis-Henriot et al., Endocrinology 1998 : Wild-type Galpha12 overexpression prevented the decrease in MAPK activity and induced MEK1, but not B-Raf , expression