Cipak et al., Neoplasma 2012
(Leukemia...) :
Inhibitors of JNK ( SP600125 ) and p38 MAPK ( SB203580 ) suppressed HEAMQ induced apoptosis and G2/M phase arrest, attenuated the activation of Bax, and blocked down-regulation of Bcl-2, XIAP and survivin in HEAMQ treated U937 cells
Fadó et al., Scientific reports 2013
(MAP Kinase Signaling System) :
The effects of XIAP are mediated by the mitogen activated protein kinase ( MEK ) /extracellular signal regulated kinases ( ERKs ) pathway since blocking this pathway completely prevents the neuritogenesis mediated by XIAP downregulation